The Rivalry Between Nomads and Settled People in Asia

The Rivalry Between Nomads and Settled People in Asia The relationship between settled peoples and nomads has been one of the great engines driving human history since the invention of agriculture and the first formation of towns and cities.  It has played out most grandly, perhaps, across the vast expanse of Asia. North African historian and philosopher Ibn Khaldun (1332-1406) writes about the dichotomy between townsfolk and nomads in The Muqaddimah.  He claims that nomads are savage and similar to wild animals, but also braver and more pure of heart than city dwellers.   Sedentary people are much concerned with all kinds of pleasures.  They are accustomed to luxury and success in worldly occupations and to indulgence in worldly desires.   By contrast, nomads go alone into the desert, guided by their fortitude, putting their trust in themselves.  Fortitude has become a character quality of theirs, and courage their nature. Neighboring groups of nomads and settled people may share bloodlines and even a common language, as with Arabic-speaking Bedouins and their citified cousins.  Throughout Asian history, however, their vastly different lifestyles and cultures have led to both periods of trade and times of conflict. Trade Between Nomads and Towns Compared with townspeople and farmers, nomads have relatively few material possessions.  Items they have to trade may include furs, meat, milk products, and livestock (such as horses).  They need metal goods such as cooking pots, knives, sewing needles, and weapons, as well as grains or fruit, cloth, and other products of sedentary life.  Lightweight luxury items, such as jewelry and silks, may have great value in nomadic cultures, as well.  Thus, there is a natural trade imbalance between the two groups. Nomads often need or want more of the goods that settled people produce than the other way around. Nomadic people have often served as traders or guides in order to earn consumer goods from their settled neighbors.  All along the Silk Road that spanned Asia, members of different nomadic or semi-nomadic peoples such as the Parthians, the Hui, and the Sogdians specialized in leading caravans across the steppes and deserts of the interior. They sold the goods in the cities of China, India, Persia, and Turkey.  On the Arabian Peninsula, the Prophet Muhammad himself was a trader and caravan leader during his early adulthood.  Traders and camel drivers served as bridges between the nomadic cultures and the cities, moving between the two worlds and conveying material wealth back to their nomadic families or clans. In some cases, settled empires established trade relations with neighboring nomadic tribes.  China often organized these relationships as a tribute. In return for acknowledging the Chinese emperors overlordship, a nomadic leader would be allowed to exchange his peoples goods for Chinese products.  During the early Han era, the nomadic Xiongnu were such a formidable threat that the tributary relationship ran in the opposite direction: the Chinese sent tribute and Chinese princesses to the Xiongnu in return for a guarantee that the nomads would not raid Han cities. Conflicts Between Settled People and Nomads When trade relations broke down, or a new nomadic tribe moved into an area, conflict erupted.  This might take the form of small raids on outlying farms or unfortified settlements.  In extreme cases, entire empires fell.  Conflict pitted the organization and resources of the settled people against the mobility and courage of the nomads.  The settled people often had thick walls and heavy guns on their side.  The nomads benefited from having very little to lose. In some cases, both sides lost when the nomads and city dwellers clashed.  The Han Chinese managed to smash the Xiongnu state in 89 CE, but the cost of fighting the nomads sent the Han Dynasty into an irreversible decline.   In other cases, the ferocity of the nomads gave them sway over vast swathes of land and numerous cities.  Genghis Khan and the Mongols built the largest land empire in history, motivated by anger over an insult from the Emir of Bukhara and by the desire for loot.  Some of Genghiss descendants, including Timur (Tamerlane) built similarly impressive records of conquest.  Despite their walls and artillery, the cities of Eurasia fell to horsemen armed with bows.   Sometimes, the nomadic peoples were so adept at conquering cities that they themselves became the emperors of settled civilizations.  The Mughal emperors of India were descended from Genghis Khan and from Timur, but they set themselves up in Delhi and Agra and became city dwellers.  They did not grow decadent and corrupt by the third generation, as Ibn Khaldun predicted, but they did go into a decline soon enough. Nomadism Today As the world grows more populated, settlements are taking over open spaces and hemming in the few remaining nomadic peoples.  Out of about seven billion humans on Earth today, only an estimated 30 million are nomadic or semi-nomadic.  Many of the remaining nomads live in Asia. Approximately 40 percent of Mongolias three million people are nomadic. In Tibet, 30 percent of the ethnic Tibetan people are nomads.  All across the Arab world, 21 million Bedouin live their traditional lifestyle.  In Pakistan and Afghanistan, 1.5 million of the Kuchi people continue to live as nomads.  Despite the Soviets best efforts, hundreds of thousands of people in Tuva, Kyrgyzstan, and Kazakhstan continue to live in yurts and follow the herds.  The Raute people of Nepal also maintain their nomadic culture, though their numbers have fallen to about 650. At present, it looks as though the forces of settlement are effectively squeezing out the nomads around the world.  However, the balance of power between city-dwellers and wanderers has shifted innumerable times in the past.  Who can say what the future holds? Sources Di Cosmo, Nicola. Ancient Inner Asian Nomads: Their Economic Basis and Its Significance in Chinese History. The Journal of Asian Studies, Vol. 53, No. 4, November 1994. Khaldun, Ibn Ibn. The Muqaddimah: An Introduction to History - Abridged Edition (Princeton Classics). Paperback, Abridged edition, Princeton University Press, April 27, 2015. Russell, Gerard. Why Nomads Win: What Ibn Khaldun Would Say about Afghanistan. Huffington Post, April 11, 2010.

Medieval Christmas Traditions

Medieval Christmas Traditions Among the Pagan traditions that have become part of Christmas is burning the yule log. This custom springs from many different cultures, but in all of them, its significance seems to lie in the iul or wheel of the year. The Druids would bless a log and keep it burning for 12 days during the winter solstice; part of the log was kept for the following year when it would be used to light the new yule log. For the Vikings, the yule log was an integral part of their celebration of the solstice, the julfest; on the log, they would carve runes representing unwanted traits (such as ill fortune or poor honor) that they wanted the gods to take from them. Wassail comes from the Old English words waes hael, which means be well, be hale, or good health. A strong, hot drink (usually a mixture of ale, honey, and spices) would be put in a large bowl, and the host would lift it and greet his companions with waes hael, to which they would reply drinc hael, which meant drink and be well. Over the centuries some non-alcoholic versions of wassail evolved. Other customs developed as part of Christian belief. For example, Mince Pies (so called because they contained shredded or minced meat) were baked in oblong casings to represent Jesus crib, and it was important to add three spices (cinnamon, cloves, and nutmeg) for the three gifts given to the Christ child by the Magi. The pies were not very large, and it was thought lucky to eat one mince pie on each of the twelve days of Christmas (ending with Epiphany, the 6th of January). Food Traditions The ever-present threat of hunger was triumphantly overcome with a feast, and in addition to the significant fare mentioned above, all manner of food would be served at Christmas. The most popular main course was goose, but many other meats were also served. Turkey was first brought to Europe from the Americas around 1520 (its earliest known consumption in England is 1541), and because it was inexpensive and quick to fatten, it rose in popularity as a Christmas feast food. Humble (or umble) pie was made from the humbles of a deer the heart, liver, brains and so forth. While the lords and ladies ate the choice cuts, the servants baked the humbles into a pie (which of course made them go further as a source of food). This appears to be the origin of the phrase, to eat humble pie. By the seventeenth century, Humble Pie had become a trademark Christmas food, as evidenced when it was outlawed along with other Christmas traditions by Oliver Cromwell and the Puritan government. The Christmas pudding of Victorian and modern times evolved from the medieval dish of frumenty a spicy, wheat-based dessert. Many other desserts were made as welcome treats for children and adults alike. Christmas Trees and Plants The tree was an important symbol to every Pagan culture. The oak, in particular, was venerated by the Druids. Evergreens, which in ancient Rome were thought to have special powers and were used for decoration, symbolized the promised return of life in the spring and came to symbolize eternal life for Christians. The Vikings hung fir and ash trees with war trophies for good luck. In the middle ages, the Church would decorate trees with apples on Christmas Eve, which they called Adam and Eve Day. However, the trees remained outdoors. In sixteenth-century Germany, it was the custom for a fir tree decorated with paper flowers to be carried through the streets on Christmas Eve to the town square, where, after a great feast and celebration that included dancing around the tree, it would be ceremonially burned. Holly, ivy, and mistletoe were all important plants to the Druids. It was believed that good spirits lived in the branches of holly. Christians believed that the berries had been white before they were turned red by Christs blood when he was made to wear the crown of thorns. Ivy was associated with the Roman god Bacchus and was not allowed by the Church as decoration until later in the middle ages when a superstition that it could help recognize witches and protect against plague arose. Entertainment Traditions Christmas may owe its popularity in medieval times to liturgical dramas and mysteries presented in the church. The most popular subject for such dramas and tropes was the Holy Family, particularly the Nativity. As interest in the Nativity grew, so did Christmas as a holiday. Carols, though very popular in the later middle ages, were at first frowned on by the Church. But, as with most popular entertainment, they eventually evolved to a suitable format, and the Church relented. The Twelve Days of Christmas may have been a game set to music. One person would sing a stanza, and another would add his own lines to the song, repeating the first persons verse. Another version states it was a Catholic catechism memory song that helped oppressed Catholics in England during the Reformation remember facts about God and Jesus at a time when practicing their faith could get them killed. (If you would like to read more about this theory, please be warned that it contains graphic descriptions of the violent nature in which Catholics were executed by the Protestant government and has been refuted as an Urban Legend.) Pantomimes and mumming were another form of popular Christmas entertainment, particularly in England. These casual plays without words usually involved dressing up as a member of the opposite gender and acting out comic stories. Note:Â  This feature originally appeared in December 1997, and was updated in December 2007 and again in December 2015.

Literature Review Essay Example | Topics and Well Written Essays - 1500 words - 1

Literature Review - Essay Example Literature related to group and teamwork will be reviewed in order to gain full insight of this particular topic and how it impacts on the behaviour of people working in an organization. This topic has been chosen since it is insightful in that it is concerned with illustrating how knowledge gained about groups affect the behaviour of people involved in order to make organizations work more effectively. The paper will also outline a personal reflection about what I have gained from studying this topic as well as areas that need further research to improve the body of knowledge that exists in this particular topic. Text analysis Why do people join groups? A group is defined as â€Å"two or more individuals, interacting and interdependent, who have come together to achieve particular objectives,† (Robbins, 1993, p. 285). On the other hand, a team is a group of people that has been formed to work together in common, coordinate their action towards the achievement of an outcome of the project for the benefit of the group (Schultz, 2005). There is no single reason why people join a group. The most popular reasons for joining a group are related to our needs for security, status, self esteem, affiliation, power and goal achievement (Robbins, 1993). People often believe that there is more strength in joining groups than standing alone (Robbins, 1993). When people work in a group, they have fewer doubts and they are more resistant to threats. For instance, new employees in an organization often vulnerable to a sense of isolation and this is the reason why the turn to the group for guidance and moral support from other seasoned employees. Other people join a group as a way of gaining status (Robbins, 1993). People tend to gain prestige for belonging to a particular group that is seen as important in an organization. It can also be observed that people belonging to a certain group also develop a sense of self esteem. The feeling of self worth is often developed by people who belong to a prestigious group that is envied by many people. The other reason why people join a group is that they need affiliation with other people (Robbins, 1993). Some people may be very reach but they cannot leave their jobs as a result of the need to interact with others. Groups often represent power and this is the reason why people often join them. What often cannot be achieved individually becomes possible if people work in groups. Essence of group or teamwork in an organization The goal of the team or group should be synergy, in other words, the sum of the individual efforts in the team is greater than the sum of the individual inputs (Schultz 2005). In an organization, people who often pull their efforts towards the attainment of the same goals are likely to succeed in their endeavour than people who work as individuals. It may be difficult for a person to achieve the same goal that can be achieved by a group of people. Basically, organizational goals can be a chieved if people work in groups. Some tasks require the efforts of many people in order for them to be achieved. The main objectives of the organization have to be shared by all the workers so that they share the same understanding towards the vision of the organization. In an organization that is characterised by teamwork, it can be seen that the employees are also motivated to pull

Organisational Behaviour AEGON Assignment Example | Topics and Well Written Essays - 1500 words

Organisational Behaviour AEGON - Assignment Example This was carried out through a launch of new products in the UK that were innovative and they captured the different financial status of the customers. Every customer, therefore, had a product they could associate with and which they could afford. The brand promotion was also carried out through changing the name of their other companies to include the name AEGON in them such as was the case for AEGON Scottish Equitable. The brand promotion also involved endorsing a British female athlete as a way to create a closer association with the same people it was trying to promote their products to. Internal forces for change The most important internal forces of change that AEGON undertook were to develop its workforce. They developed the skills of its workers to match the needs of the customers. This way, the employees were well equipped to handle the customers’ needs as well as the new products that were developed. The organization in the other successful nations such as in the US is renowned for its employees that are experts, innovative and have good communication skills. This was what the organization wanted its UK-based employees to be renowned for as another way to attract more customers hence increasing their skills. AEGON could not expect to make any changes externally without having to change their culture which was making them fail to get established in the UK in the first place. Culture change involved the employees and managers changing their attitude, behavior, values as well as belief.

Properties of Some Ayurvedic Bhasmas

Properties of Some Ayurvedic Bhasmas Investigation of Structure, Microbiological and Cytotoxic Properties of Some Ayurvedic Bhasmas Introduction Ayurveda is the traditional Hindu medicine system practiced extensively in South Asia. In Sanskrit, the word Ayurveda is basically made of two components, Ayush life and Veda science and knowledge. This states clearly that science of life is Ayurveda. From ancient period Ayurvedic medicine is in use with the objectives: i) to enhance health status physically, mentally and spiritually free of illness and ii) to cure disease with the help of natural diet, medicine. In ancient period if people get sick and injured there was a trend of use of medicine which is also known as folk medicine. Use of Bhasmas as Ayurvedic medicine has been known from as an alternative medicine. Use of traditional medicine includes Ayurveda, Ancient Iraninan, Korean and African medicine. But recently WHO has noticed that use of these medicines in inappropriate way may give some negative and toxic results. And research work is to be done for its safety and ascertinity. These days microorganisms are common org anisms for causing disease (Shubha Hiremath, 2010). Some of them can be cured with daily hygienic processes but most of them can be removed and recovered with the use of medicines. Ayurveda is the traditional Hindu medicine system practiced extensively in South Asia. Ayurvedic medicine has wide range of composition, which also includes Bhasmas. Literally, Bhasma is something that is obtained from the process of calcination. Generally, calcination and incineration of any gem or metal substance is performed to prepare such formulations and used in any medicinal purpose as Ayurvedic medicine (Kumar Pal, 2015). The Bhasmas are prepared from metals like gold, silver, iron, lead, mercury and arsenic and so on (see Tables 1 and 2). Metal constituent are supposed to have positive impact to human health through Ayurvedic perspective. However, in modern synthetic medicine heavy metal are considered toxic. The objective of this study is to test the impacts of these drugs on growth of microorganism. Lead, mercury and arsenic is considered as the harmful compound that may lead to different kinds of disease especially cancer (Patra, Bhattacharya, Mukhopadhyay, Mukherjee, 2010). The aim in this work is to analyze the selected Bhasma drugs with respect to their structure, perform their antimicrobial susceptibility tests and also to analyze the cytotoxic effect towards the cell lines. Furthermore, if there is any antimicrobial and cytotoxic behavior of the drugs, the attempts will be made to answer the following questions: Is the given Bhasmas effect related to the presence of heavy metal compound? Is the effect the result of other materials that has been added for the preparation of that Ayurvedic Bhasma? Table 1. Some of the Bhasmas intended to be studied in the proposed work S. No. Name of Bhasma Content (metal) 1 Parad Mercury 2 Hartal Arsenic 3 Manoshila Arsenic 4 Naag Lead 5 Shisak Lead 6 Kajjali Mercury 7 Ras sindur Mercury 8 Kajjali Mercury 9 Jasada Zinc 10 Loha Iron 11 Rajat Silver 12 Sworna Gold Tabl 2: Some Bhasmas that are produced by calcination of corresponding mineral compounds S. No. Name Source 1 Coury Cowry shell 2 Abraka Mica 3 Muga Coral 4 Sankha Conch shell 5 Sipi Oyster shell 6 Moti Pearl shell Ayurveda is an ancient Indian system of medicine dating back to 5000BC. Literally the science of life, it uses animal, plant, mineral and metal based medicines to cure diseases. (Barve, Mashru, Jagtap, Pargiri, Prajapati, 2011) (Patwardhan Mashelkar, 2009) A part of Ayurveda called Rasasatra is concerned with drugs of the metal-mineral origin, their processing technique, properties and therapeutic applications (Sarkar, Das, Prajapati, 2010). In Ayurveda, the drugs with mineral origin are considered more effective than those of animal and plant origin. Generally, metal minerals in the original form are toxic, non-absorbable and dont have medicinal significance. Therefore, are transformed by various standard protocols before being used as drug. Pharmaceuticals with the metal minerals origin are called Bhasmas. Bhasmas is a calcined powder of mineral, metal, gems (Sangale, Suryawanshi, Chikate, Khot, 2014). Sworna (Gold) Bhasmas, Rajata (Silver) Bhasmas, Tamra (Copper) Bhasma, Loha (Iron) Bhasmas, Jasada (Zinc) Bhasmas and ashes of the minerals like Caury (cowry shells), Muga (corals), Sankha (conch shell), Sipi (oyster shell) and others have been extensively used as Bhasmas in Ayurvedic medicine (Adhikari, 2014) (Krishnamachary, et al., 2012) (Sarkar, Das, Prajapati, 2010) (Wadekar, Rode, Bendale, Patil, Prabhune, 2005). The importance of the proper dose and way of administration of Ayurvedic drugs has been studied. It has been found that improper application of the Bhasmas lead to the death of the patients. The death is due to the accumulation of the heavy metals in the soft cells (Sarkar, Das, Prajapati, 2010) (Kapoor, 2010). However, heavy metals are drugs if they are supplied within recommended limits on their labels for plant and animal. Preparation methods determine the therapeutic efficiency as well as level of toxicity of the Bhasmas (Nagarajan, Rajan, Krishnan, Sethuraman, 2014). Formulation of Bhasmas based on standard protocol reveals nanostructured morphology. These metallic nanoparticles are taken along with milk, butter, honey, ghee which eliminate their harmful effects and intensify their biocompatibility (Formulation, 2014). Jasada Bhasma has been used for treatment of diabetes, arthritis and tuberculosis. Rajata Bhasma is used to cure muscles wasting, brain diseases and nervous disorder. Similarly, Sworna Bhasma is used for arthritis and rheumatoid (Adhikari, 2014) (Patwardhan Mashelkar, 2009). These are the ancient formulation of the metal and minerals based drugs in Ayurveda. In modern medicine, the trend of the using the metal nanoparticle is increasing for curing diseases. Modern nanoparticles through a several chemical modifications are used in the preparation of the nanodrugs. Recent trend on modern medicine shows that nanoparticles from gold, silver, iron, zinc can be used against several chronic diseases. Gold nanoparticles have high therapeu tic potential to fight against cancer and act as drug delivery vehicles (Khan, Vishakante, Siddaramaiah, 2013) (Dobrovolskaia McNeil, 2007) (Patra, Bhattacharya, Mukhopadhyay, Mukherjee, 2010). Therefore, the systematic studies of the many Bhasmas are still behind the horizon. Such Bhasmas may have potential for higher therapeutic values for curing chronic diseases. So, to investigate the science behind the different Ayurvedic Bhasmas, in particular with respect to their structiure-properties correlations, and their medicinal values will be the topic of the proposed project. The proposed research will encompass different interesting questions which will be attempted to solve in the course of the study. What is the physico-chemical and microscopic structure of the given Bhama? Is it a kind of nanomedicine with respect to its structure? What is the real chemical compositions? How do Bhasmas differ with respect to their microbiological effects on the human body? Will the Bhasma show significant cytotoxic effect only towards diseased cells? How will the normal cell lines respond? Can a correlation be established between the structure and properties of the Bhasmas? Although heavy metals have proved poisonous effects and have a predominantly unfavorable reputation in the modern scientific society, these have been used as pharmaceutical agents since first century B.C. Traditional literature like Rasatarangini, Charaksamita, Rasratnasammuchaya compiled the processing, manufacturing and therapeutic application of heavy metal containing drugs. Different studies show that formulation with heavy metal has toxic effect. The toxicity level depends upon various factors such as processing of raw materials, method and amount of consumption. Heavy metals with nanoscopic structure are generally absorbable inside cell. Recent trend also shows that nanoparticles of gold, arsenic, silver have pharmaceutical potentiality. Thats why well documented study on Bhasmas prepared from heavy metals is needed for their appropriate use as well as for the proper understanding of their structure-properties relationships. Preliminary works have been performed in a variety of Ayurvedic drugs including some drugs comprising Arsenic compounds (Harital) by the research group comprising the some of these members of the present consortium (Panta, Bhandari and Lamsal, and Adhikari 2017). Microscopic, spectroscopic and antibacterial tests were performed on some of the drugs. The compounds exhibited quite strong antibacterial activities again gram positive and gram negative bacteria. Nanomechanical aspects of the Bhamsa drugs were also review some time ago to find the parallel between modern nanomedicine and ancient ayurvedic Bhasma (Adhikari, 2014). Thus, there is a sufficient background information and nalaytical skill in the research group to perform successfully the proposed research works. The proposed work is aimed at the investigation of physico-chemical structure as well as microbiological and cytotoxic properties of different Bhasmas. To elucidate the composition and structure of Bhasma. To see the positive effect of components, present in Bhasma. To study the toxicity of Bhasma on microorganisms and cell lines. To bridge the gap between modern medicine and traditional medicine practice. The research will begin with detail literature survey to eliminate the possibility of duplication and to determine possibility of conflict of interest. The commercial Bhasma will be collected and sample preparation will be done in accordance to the availability of Bhasma in the market while strictly following the procedure described in the Ayurvedic books. Pertinent physical and chemical properties will be studied and the sample will be sent for characterization. X-Ray Diffraction, Optical Microscopy, Electron Microscopy and Spectroscopic Analysis will be performed. After characterization, based on the composition, the proper solvent for the drugs to enter the cell will be selected. Biological assay will then be carried out according to standard protocol. The assays include anti-microbial, cytotoxicity and antidiabetic. The obtained results of all above tests will be compile and analyzed manually or using computer software wherever applicable. The report will then be prepared. The ab ove process is illustrated in the flowchart below. The research plan including the anylytical procedure is depicted in Scheme 1. Scheme 1: Flowsheet depicting the analytical and research plan for the proposed work         Ã‚   It has been proved by earlier studies that the Bhasmas prepared after using standard protocol should reveal nanoparticles which are thus expected to show anti-microbial activity against pathogenic bacteria and fungi. It is the topic to explorer the opportunities that the Bhasmas might exhibit pharmaceutical potentiality against cancer, diabetic and HIV/ AIDS. This study is expected to deliver the following outcome after completion of the works. Provide necessary scientific foundation for structure and composition of the Bhasmas. This study may be able to clarify the issue of contradiction related to the statement telling Ayurvedic formulations with heavy metals are toxic to health. The study will deliver the structure-antibacterial properties correlations of very important traditional medicinal practice of the country. Limitations This study does not cover any Ayurvedic formulation based on herbs and animals. This research does not include detail mechanism of action of the Bhasmas on tested parameters. This work does not associate in any way to the psychological, psychiatric and social impacts that might arrive after the use of Bhasmas. Delimitations This project will bring Ayurveda from supplemental medicine to main stream treatment practice. This work may change the notion that heavy metals in all form are detrimental to health. The facilities available in the laboratory in the REACST will be primarily sufficient for performing major part of the study. Some of the samples have to be sent to other laboratories. This study associates with a variety of people who have been working with Bhasmas as family business for many generations. The result of this work, if contradicting with their practices, might affect their livelihood. The formulation of Bhasmas will be done in isolated condition using standard protocol and also focus to minimize metal hazards during study. This project does not incorporate all the aspects of heavy metals impact in body. Thus, any action based solely on this work might cause on foreseen effects. S.N Task to be done Tentative time 1 Literature review 8 weeks 2 Chemical and instrument collection 4 weeks 3 Commercial sample collection 4 weeks 4 Sample preparation 16 weeks 5 Characterization 16 weeks 6 Biological Assay Antimicrobial test 4 weeks Cytotoxicity (Anti-cancer) 6 weeks Anti-diabetic 10 weeks 7 Data Analysis 8 weeks 8 Preparation of initial draft of report 8 weeks 9 Finalization of report 12 weeks Total Time 96 weeks = 1 year 10 month Estimated Budget S. No. Title Amount (Rs.) 1. Chemical Formulation Rs. 30,000/- Antimicrobial test Rs. 30,000/- Cytotoxicity test Rs. 40,000/- Antidiabetics test Rs. 40,000/- 2. Instruments Rs. 1,50,000/- 3. Commercial Sample Rs. 10,000/- 4. Transportation and Courier for Characterization Rs. 40,000/- 5. Stationary and Logistics Rs. 30,000/- 6. Miscellaneous (printing, binding, communications etc.) Rs. 20,000/- 7. Laboratory chemicals Rs. 60,000/- Total Rs. 4,50,000/- Today nano-medicine is emerging as new revolution worldwide and has several promises. The exploration of nano-formulations in medical field has made us to dream of several opportunities. The study of the Bhasmas will help to gain those goals. There is higher chance of innovation of new drugs by mixing the indigenous knowledge with modern technology of drug discovery and delivery. These efforts on Bhasmas are directed toward finding solution to crucial issues of infectious disease and in particular tackling with more vulnerability the comeback of diabetics, HIV/AIDS and the devastating spread of cancer in world. However, more effort has to be done to uplift the potentiality of Bhasmas to that of modern nanodrugs. More research is desirable which explore the co-relation between structural nature and mechanism associated with their therapeutic activity. This study can provide pathway to enhance the use of traditional Ayurvedic medicine and helps to preserve the traditional knowledge. References       Adhikari, R. (2014). Ayurvedic Bhasmas: Overview on Nanomaterialistic Aspects, Applications, and Perspectives. Infectious Diseases and Nanomedicine I, 23-32. doi:10.1007/978-81-322-1777-0_3 Barve, M., Mashru, M., Jagtap, C., Pargiri, B. J., Prajapati, P. K. (2011). Therapuetic potentials of metals in ancient India: A review through Charaka Samhita. Journal of Ayurveda and Intregative Medicine, 2(2), 55-63. Retrieved from http://imsear.hellis.org/handle/123456789/172982 Dobrovolskaia, M. A., McNeil, S. E. (2007). Immunological properties of engineered nanomaterials. Nature nanotechnology, 2(8), 469-478. doi:10.1038/nnano.2007.223 Formulation, c. a.-m. (2014). Rasheed, Arun; Naik, Madhu; Haneefa, Kotappadath Pillanayil Mohammed; Kumar, Raveendran Pillai Arun; Azeem, Abdul Kharim. Pak. J. Pharm. Sci, 27(4), 793-800. Retrieved from http://applications.emro.who.int/imemrf/Pak_J_Pharm_Sci/Pak_J_Pharm_Sci_2014_27_4_793_800.pdf Kapoor, R. C. (2010). Some observations on the metal-based preparations in Indian systems of medicine. Indian Journal of Traditional Knowledge, 9(3). Retrieved from http://hdl.handle.net/2248/3544 Khan, M. S., Vishakante, G. D., Siddaramaiah, H. (2013). Gold nanoparticles: a paradigm shift in biomedical applications. Advances in colloid and interface science, 199, 44-58. doi:10.1016/j.cis.2013.06.003 Krishnamachary, B., Rajendran, N., Pemiah, B., Krishnaswamy, S., Krishnan, U. M., Sethuraman, S., Sekar, R. K. (2012). Scientific validation of the different purification steps involved in the preparation of an Indian Ayurvedic medicine, Lauha bhasma. Journal of ethnopharmacology, 142(1), 98-104. doi:10.1016/j.jep.2012.04.021 Kumar Pal, S. (2015). The Ayurvedic Bhasma: The Ancient Science of Nanomedicine. Recent Patents on Nanomedicine, 5(1), 12-18. Nagarajan, S. a., Rajan, K., Krishnan, U., Sethuraman, S. (2014). Scientific insights in the preparation and characterisation of a lead-based naga bhasma. Indian journal of pharmaceutical sciences, 76(1), 38-45. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007254/ Panta, P, Bhandari, T. R, Lamsal B., and Adhikari, R. unpublished results (2017) Patra, C. R., Bhattacharya, R., Mukhopadhyay, D., Mukherjee, P. (2010). Fabrication of gold nanoparticles for targeted therapy in pancreatic cancer. Advanced drug delivery reviews, 62(3), 346-361. doi:10.1016/j.addr.2009.11.007 Patwardhan, B., Mashelkar, R. A. (2009). Traditional medicine-inspired approaches to drug discovery: Can Ayurveda show the way forward. Drug discovery today, 14(15), 804-811. doi:10.1016/j.drudis.2009.05.009 Sangale, M. D., Suryawanshi, M., Chikate, C., Khot, R. (2014). Comparative studies and analysis of Jasandand Nag bhasma prepared by different Ayurvedic pharmaceuticals. International Journal of Advanced Scientific and Technical Research, 2(4). Retrieved from http://rspublication.com/ijst/2014/april14/29.pdf Sarkar, P. K., Das, S., Prajapati, P. K. (2010). Ancient concept of metal pharmacology based on Ayurvedic literature. Ancient science of life, 29(4), 1-6. Shubha, S. H., Hiremath, R. S. (2010). Evaluation of antimicrobial activity of Rasaka Bhasma. AYU: An International Quarterly Journal of Research in Ayurveda, 31(2), 260-262. Wadekar, M. P., Rode, C. V., Bendale, Y. N., Patil, K. R., Prabhune, A. A. (2005). Preparation and characterization of a copper based Indian traditional drug: Tamra bhasma. Journal of Pharmaceutical and Biomedical Analysis, 39(5), 951-955. doi:10.1016/j.jpba.2005.06.015 Association to national Priority Ayurvedic drugs are indigenous technology of Nepal. The practice incorporates a wide variety of social groups during the raw material collection, purification, processing, delivery and prescription of medicine. Moreover, the need of raw materials opens door to industrial and entrepreneur investment. The work we have proposed thus can impact a variety of national priority which will be described in detail below Bhasma is found to have significant effect on the cure of tuberculosis. They are also expected to cure diabetes, cancer and other non-communicable diseases. The reduction of these communicable and non-communicable disease is a part of the Sustainable Development Goal (SDG). The formulations studied in our work can play a major role in meeting the SDG as well as in improving the health indicators not covered in SDG but is a common health problem in Nepal such as rheumatic and skin disease [SDG] The production and dissemination of Bhasma is a multi-step process requiring a variety of manpower. It demands unskilled manpower for labor works necessary in all steps, semi-skilled manpower for the production and distribution of medicines as well as skilled manpower like doctors, chemists, administrators to supervise the whole operation. Hence understanding and commercialization of Bhasma can significantly contribute to employ not only local manpower but also help bring back the manpower currently outside Nepal. Bhasma is unquestionably the local intellectual property of Nepal which requires protection before it becomes the victim of modern medicine hegemony and foreign trademark. This work will be a step to the documentation, standardization and recognition of the ancient knowledge which is not yet accepted as a scientific truth. Understanding and patenting the rights in the country will prevent local knowledge from being foreign property. This project is also a step towards proper documentation and preservation of rare and endangered books. Preparation of Bhasma is a traditional example of top-down nanofabrication. Nanoscience and nanotechnology is a burning research field. However, only a handful of work has been done in this field. Government as well as private investors are reluctant to investment on nanoscience. This project can be an invitation to industries as well as academia to focus on nanomaterial synthesis and use to solution of everyday problem.

Early Humans Essay

What animals did the early humans hunt for food? Early humans found meat from animals that were back in the day, the meat was not so common because before they had animals they had other types of food like for example, fruits from trees, nuts and sometimes even honey and the y also got berries form the burry bushes like raspberries, strawberries, blueberries and so on, but the animal that they always use to eat in the ancient times was the buffalo which was one of the most common animals in there specific villages and mostly when they would get the animals they would open them up with sharp things and then they would eat the meat and by the time they figured out fire they used fire to cook the food like we do know. How the early Human nut and got their food? Well the simple answer is that they used weapon to hunt the animals but we always thought that the early humans are stupid but the truth is that they are actually very smart because of the weapons they used for hunting and another thing they did to hunt food was that back in the early days there was a group of people called hunter gatherers and what hunter gatherers are is that basically a group of people for example from villages (mostly man) would go out to hunt for food mostly everyday and then when any of them would get food they will bring it to the group of people that they are and then the would most probably share the food with the people. And mostly the weapons would be made out of stones and wood. Also an example of the weapons they used wear spears and bows made out wood and stones. The most common food eaten nowadyaus are seeds. Also very populare is vegetables and fruits.

International Business-Level Strategy and International Corporate-Level Strategy of Apple Inc Free Essay Example, 1500 words

The firm was established by Steve Jobs in the year 1975 with the sole aim of developing and selling personal computers. It was fully incorporated in 1977 and renamed Apple Inc. so as to show its focus on the manufacture of major electronics. It is the second leading firm in the world of information technology after the giant Samsung. Currently, Apple has managed to acquire a total of 62 companies and has proceeded to purchase stakes in the other two companies. One of the philosophies of the company is to acquire as many small firms as possible and to integrate them into its big goal and projects. The first acquisition was made in the year 1988 with the purchase of Network Innovations and the highest number of the acquisition was attained in the year 2013 in which it acquired a total of 13 firms. The most expensive acquisition by Apple was done this year in the month of August when t acquired Beats Electronics at a cost of US$3 billion. 46 out of the 62 acquisitions and mergers by A pple has been on the firms in the United States. We will write a custom essay sample on International Business-Level Strategy and International Corporate-Level Strategy of Apple Inc or any topic specifically for you Only $17.96 $11.86/page